Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.57 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329822 | 0.86 | PKM (0.61) | TP53KDM4EMAPTSAE1UBA2 | |
| SCHEMBL5331673 | 0.82 | KDM4E (0.62) | TP53KDM4EMAPTSAE1UBA2 | |
| SCHEMBL5326933 | 0.80 | KDM4E (0.50) | TP53KDM4EMAPTSAE1UBA2 | |
| SCHEMBL5327554 | 0.80 | PTGDR2 (0.81) | TP53KDM4EMAPTSAE1UBA2 | |
| SCHEMBL5328927 | 0.80 | PTGDR2 (0.64) | TP53KDM4EMAPTSAE1UBA2 | |
| SCHEMBL5325062 | 0.78 | KDM4E (0.59) | KDM4EMAPTSAE1UBA2PTGDR2 | |
| SCHEMBL27826430 | 0.78 | PLA2G2A (0.42) | TP53KDM4EMAPTSAE1UBA2 | |
| SCHEMBL5329826 | 0.76 | KDM4E (0.68) | KDM4EMAPTSAE1UBA2PTGDR2 | |
| SCHEMBL6583766 | 0.75 | KDM4E (0.77) | TP53KDM4EMAPTPTGDR2ALDH1A1 | |
| SCHEMBL5334050 | 0.75 | BRD4 (0.61) | KDM4EMAPTSAE1UBA2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |