Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.81 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14346980 | 0.90 | PTGDR2 (1.00) | PTGDR2TP53KDM4EMAPTSAE1 | |
| SCHEMBL5328927 | 0.88 | PTGDR2 (0.64) | PTGDR2TP53KDM4EMAPTSAE1 | |
| SCHEMBL5331673 | 0.82 | KDM4E (0.62) | PTGDR2TP53KDM4EMAPTSAE1 | |
| SCHEMBL5329822 | 0.82 | PKM (0.61) | PTGDR2TP53KDM4EMAPTSAE1 | |
| SCHEMBL5327558 | 0.80 | TP53 (0.58) | PTGDR2TP53KDM4EMAPTSAE1 | |
| SCHEMBL14346730 | 0.79 | PTGDR2 (0.79) | PTGDR2KDM4EMAPTSAE1UBA2 | |
| SCHEMBL3344758 | 0.79 | PTGDR2 (0.51) | PTGDR2TP53KDM4EMAPTALDH1A1 | |
| SCHEMBL3348106 | 0.77 | PTGDR2 (0.49) | PTGDR2KDM4EMAPTALDH1A1PKM | |
| SCHEMBL3780495 | 0.76 | PTGDR2 (0.48) | PTGDR2KDM4ELMNANPSR1KMT2A | |
| SCHEMBL3344745 | 0.76 | PTGDR2 (0.48) | PTGDR2KDM4EMAPTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |