Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23023788 | 0.92 | OPRM1 (0.47) | SLC6A4 | |
| SCHEMBL28320698 | 0.83 | SSTR4 (0.46) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL294762 | 0.79 | OPRM1 (0.61) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL24997817 | 0.78 | ALDH1A1 (0.41) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL28148666 | 0.78 | OPRM1 (0.59) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL294583 | 0.77 | OPRM1 (0.63) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL6114268 | 0.75 | GRIN2D (0.49) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| Eticyclidine SCHEMBL66697 | 0.74 | GRIN2D (0.57) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL26031783 | 0.73 | HDAC3 (0.39) | SLC6A4SLC6A3 | |
| SCHEMBL23595634 | 0.73 | LMNA (0.34) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141600-A1 | CURRENT DEPENDENT NMDA ANTAGONISTS | BARTH FREDERIK H (DE) | 2007-12-13 | — | — | WO | disclosed |