Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.51 |
| ▸ | PPARD | Q03181 | 10/20 | 0.51 |
| ▸ | PPARG | P37231 | 8/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5436500 | 0.83 | PPARA (0.60) | PPARAPPARDPPARG | |
| SCHEMBL5327164 | 0.82 | PPARA (0.54) | PPARAPPARDPPARGIDH1 | |
| SCHEMBL5327749 | 0.82 | PPARA (0.45) | PPARAPPARDPPARG | |
| SCHEMBL14345479 | 0.78 | MAPT (0.55) | PPARAPPARDPPARG | |
| SCHEMBL14345282 | 0.78 | KMT2A (0.48) | PPARAPPARDPPARG | |
| SCHEMBL14345132 | 0.78 | IDH1 (0.55) | PPARAPPARDPPARGIDH1 | |
| SCHEMBL6558040 | 0.77 | ALDH1A1 (0.63) | PPARAPPARG | |
| SCHEMBL6555958 | 0.77 | PPARA (0.57) | PPARAPPARDPPARG | |
| SCHEMBL2656816 | 0.76 | PPARA (0.54) | PPARAPPARDPPARG | |
| SCHEMBL14345585 | 0.76 | PPARA (0.60) | PPARAPPARDPPARGIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141423-A1 | PPAR ENHANCING DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | NEGMA-LERADS (FR) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007141423-A1 | PPAR ENHANCING DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | NEGMA-LERADS (FR) | 2007-12-13 | — | — | WO | disclosed |