Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 9/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345534 | 0.85 | MEN1 (0.58) | KMT2AMEN1PPARAGAAMAPT | |
| SCHEMBL8926644 | 0.79 | KMT2A (0.64) | KMT2AMEN1PPARAPPARGHPGD | |
| SCHEMBL5328307 | 0.78 | POLB (0.52) | KMT2AMEN1PPARAPPARGNPC1 | |
| SCHEMBL5327752 | 0.78 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5342673 | 0.76 | NPC1 (0.65) | KMT2AMEN1HPGDGAANPC1 | |
| SCHEMBL6359190 | 0.75 | PPARA (0.61) | KMT2AMEN1PPARAPPARGGAA | |
| SCHEMBL8925777 | 0.74 | PPARA (0.62) | KMT2AMEN1PPARAPPARGGAA | |
| SCHEMBL8768931 | 0.74 | PPARA (0.52) | PPARAPPARGGAANPC1RAB9A | |
| SCHEMBL14345525 | 0.74 | PPARA (0.56) | KMT2AMEN1PPARAPPARGGAA | |
| SCHEMBL14345590 | 0.73 | PPARA (0.53) | KMT2AMEN1PPARAPPARGGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141423-A1 | PPAR ENHANCING DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | NEGMA-LERADS (FR) | 2007-12-13 | — | — | WO | disclosed |