Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL17797781 | 1.00 | TSHR (0.58) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL31485057 | 0.91 | TSHR (0.55) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL87786 | 0.91 | TSHR (0.55) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL3262300 | 0.90 | DAO (0.52) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL9862718 | 0.89 | KMO (0.47) | TSHRDAONAPRTCES1CES2 | |
| Isophthalic Acid SCHEMBL17628646 | 0.88 | KMO (0.50) | TSHRDAONAPRTCYP2C9MEN1 | |
| Terephthalic Acid SCHEMBL28820897 | 0.88 | TSHR (0.50) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL2206532 | 0.88 | TSHR (0.50) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL27707378 | 0.88 | TSHR (0.50) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL7604226 | 0.85 | DAO (0.50) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860863-B1 | METHOD FOR CREATING A SECURITY ELEMENT ON SECURITY DOCUMENTS AND SECURITY DOCUMENT CONTAINING SECURITY ELEMENT | ANY BIZTONSAGI NYOMDA NYRT (HU) | 2024-08-21 | — | — | EP | claimed |
| CN-112639044-A | Compostable hot melt adhesive | 波士胶公司 | 2021-04-09 | — | — | CN | claimed |
| US-9587086-B2 | Poly(vinyl acetal) resin compositions, layers, and interlayers having enhanced optical properties | EASTMAN CHEMICAL COMPANY (US) | 2017-03-07 | — | — | US | claimed |
| US-20160160005-A1 | POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES | SOLUTION INC. (US) | 2016-06-09 | — | — | US | claimed |
| US-9200137-B2 | Compositions comprising structural isomers of 1,4-cyclohexanedimethanol dibenzoate and polymer compositions containing same | EASTMAN SPECIALTIES HOLDINGS CORPORATION (US) | 2015-12-01 | — | — | US | claimed |
| EP-2694609-B1 | POLYOLEFIN BASED HOT MELT ADHESIVE CONTAINING A SOLID PLASTICIZER | BOSTIK INC (US) | 2015-08-19 | — | — | EP | claimed |
| EP-2709982-B1 | POWDERY PEROXIDE COMPOSITIONS ACCEPTABLE FOR OCCUPATIONAL HEALTH | PERGAN GmbH (DE) | 2015-02-18 | — | — | EP | claimed |
| US-20130237939-A1 | NOVEL COMPOSITIONS COMPRISING STRUCTURAL ISOMERS OF 1,4-CYCLOHEXANEDIMETHANOL DIBENZOATE AND POLYMER COMPOSITIONS CONTAINING SAME | EASTMAN SPECIALTIES HOLDINGS CORPORATION (US) | 2013-09-12 | — | — | US | claimed |
| US-8431232-B2 | Aromatic-aliphatic polyester hot melt adhesives for roll-applied labels | EASTMAN CHEMICAL COMPANY (US) | 2013-04-30 | — | — | US | claimed |
| US-8389117-B2 | Hot melt adhesives for roll-applied labels | EASTMAN CHEMICAL COMPANY (US) | 2013-03-05 | — | — | US | claimed |
| EP-2222460-A1 | NOVEL COMPOSITIONS COMPRISING STRUCTURAL ISOMERS OF 1,4-CYCLOHEXANEDIMETHANOL DIBENZOATE AND POLYMER COMPOSITIONS CONTAINING SAME | Genovique Specialties Holdings Corporation (US) | 2010-09-01 | — | — | EP | claimed |
| WO-2010056271-A1 | AROMATIC-ALIPHATIC POLYESTER HOT MELT ADHESIVES FOR ROLL-APPLIED LABELS | EASTMAN CHEMICAL COMPANY (US) | 2010-05-20 | — | — | WO | claimed |
| WO-2010056270-A1 | HOT MELT ADHESIVES FOR ROLL-APPLIED LABELS | EASTMAN CHEMICAL COMPANY (US) | 2010-05-20 | — | — | WO | claimed |
| US-20100112251-A1 | AROMATIC-ALIPHATIC POLYESTER HOT MELT ADHESIVES FOR ROLL-APPLIED LABELS | EASTMAN CHEMICAL COMPANY (US) | 2010-05-06 | — | — | US | claimed |
| US-20100112250-A1 | HOT MELT ADHESIVES FOR ROLL-APPLIED LABELS | EASTMAN CHEMICAL COMPANY (US) | 2010-05-06 | — | — | US | claimed |
| WO-2009073393-A1 | NOVEL COMPOSITIONS COMPRISING STRUCTURAL ISOMERS OF 1,4-CYCLOHEXANEDIMETHANOL DIBENZOATE AND POLYMER COMPOSITIONS CONTAINING SAME | GENOVIQUE SPECIALTIES HOLDINGS CORPORATION (US) | 2009-06-11 | — | — | WO | claimed |
| US-20090142981-A1 | Novel Compositions Comprising Structural Isomers Of 1,4-Cyclohexanedimethanol Dibenzoate and Polymer Compositions Containing Same | VELSICOL CHEMICAL CORPORATION (US) | 2009-06-04 | — | — | US | claimed |
| EP-1629988-B1 | Fusible inkjet media including solid plasticizer particles and methods of forming and using the fusible inkjet media | HEWLETT PACKARD DEVELOPMENT CO (US) | 2008-12-24 | — | — | EP | claimed |
| EP-1629988-A2 | Fusible inkjet media including solid plasticizer particles and methods of forming and using the fusible inkjet media | Hewlett-Packard Development Company, L.P. (US) | 2006-03-01 | — | — | EP | claimed |
| US-20060038871-A1 | Fusible inkjet media including solid plasticizer particles and methods of forming and using the fusible inkjet media | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2006-02-23 | — | — | US | claimed |