Terephthalic Acid

Terephthalic Acid

SCHEMBL87786

O=C(O)c1ccc(C(=O)O)cc1.OCC1CCC(CO)CC1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
TP53 P04637 1/20 0.55
SRD5A2 P31213 4/20 0.48
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA12 O43570 1/20 0.46
CA3 P07451 1/20 0.46
TYR P14679 1/20 0.46
DRD1 P21728 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
ALDH1A1 P00352 2/20 0.45
KMT2A Q03164 2/20 0.44
ALOX15 P16050 1/20 0.44
TPMT P51580 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL31485057 1.00 TSHR (0.55) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL2206532 0.96 TSHR (0.50) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL27707378 0.96 TSHR (0.50) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL28820897 0.96 TSHR (0.50) TSHRTP53SRD5A2CA1CA2
Benzoic Acid SCHEMBL17797781 0.91 TSHR (0.58) TSHRTP53SRD5A2ALDH1A1KMT2A
Benzoic Acid SCHEMBL532786 0.91 TSHR (0.58) TSHRTP53SRD5A2ALDH1A1KMT2A
Terephthalic Acid SCHEMBL14657242 0.90 USP2 (0.53) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL6442298 0.90 KMT2A (0.55) TSHRTP53SRD5A2KMT2A
Terephthalic Acid SCHEMBL9862718 0.89 KMO (0.47) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL27981592 0.86 TSHR (0.40) TSHRTP53SRD5A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4242 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120590687-B Flame retardant additive, polyester resin composition containing flame retardant additive and application of flame retardant additive 辽宁金发生物材料有限公司 2026-05-22 CN claimed
CN-122011702-A Polyester resin composition and preparation method thereof 江苏欣宝科技股份有限公司 2026-05-12 CN claimed
CN-122029225-A Flame retardant compositions with improved electrical properties and hydrolytic stability 科莱恩国际有限公司 2026-05-12 CN claimed
EP-4522686-B1 CREEP-RESISTANT POLYESTER COMPOSITIONS ENVALIOR DEUTSCHLAND GMBH (DE) 2026-05-06 EP claimed
EP-3585833-B1 EFFICIENT PHOSPHOROUS STABILISERS BASED ON DIPHENYLAMINE AND HETEROCYCLIC DIPHENYLAMINE DERIVATIVES FRAUNHOFER GES FORSCHUNG (DE) 2026-04-01 EP claimed
US-20260085164-A1 HIGH MECHANICAL STRENGTH POLYMER THIN FILM, MANUFACTURING METHOD THEREFOR, AND USE THEREOF YANGZHOU NANOPORE INNOVATIVE MATERIALS TECHNOLOGY LTD. (CN) 2026-03-26 US claimed
US-20250349904-A1 SOLID-STATE BATTERY CELL ASSEMBLY AND PREPARATION METHOD THEREFOR, BATTERY, AND APPLICATION THEREOF CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2025-11-13 US claimed
EP-3658616-B1 HALOGEN-FREE SULPHONIC ACID ESTER AND/OR SULPHINIC ACID ESTER AS FLAME RETARDANT, FLAME RETARDANT SYNERGISTS AND RADICAL GENERATORS IN PLASTICS FRAUNHOFER GES FORSCHUNG (DE) 2025-10-22 EP claimed
EP-4632931-A1 SOLID-STATE BATTERY CELL ASSEMBLY AND PREPARATION METHOD THEREFOR, AND BATTERY AND APPLICATION THEREOF Contemporary Amperex Technology Co., Limited (CN) 2025-10-15 EP claimed
US-20250304767-A1 CREEP-RESISTANT POLYESTER COMPOSITIONS ENVALIOR DEUTSCHLAND GMBH (DE) 2025-10-02 US claimed
EP-0712899-A1 Hydrolytic stable glass fiber reinforced polyester resins GENERAL ELECTRIC COMPANY (US) 1996-05-22 EP claimed
EP-0591391-B1 PEELABLE SEAL COMPOSITIONS DU PONT (US) 1995-07-12 EP claimed
EP-0644226-A1 EASILY TEARABLE FILM AND METHOD OF MANUFACTURING THE SAME DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1995-03-22 EP claimed
EP-0591391-A1 PEELABLE SEAL COMPOSITIONS. DU PONT (US) 1994-04-13 EP claimed
EP-0542464-A1 Polycarbonate resin composition GENERAL ELECTRIC COMPANY (US) 1993-05-19 EP claimed
WO-1993000403-A1 PEELABLE SEAL COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-01-07 WO claimed
EP-0502960-A1 FILM LAMINATE EASTMAN KODAK COMPANY (US) 1992-09-16 EP claimed
US-5034263-A Polyesters EASTMAN KODAK COMPANY (US) 1991-07-23 US claimed
WO-1991008107-A1 FILM LAMINATE EASTMAN KODAK COMPANY (US) 1991-06-13 WO claimed
US-4146674-A FOR PILLOWS BAYER AKTIENGESELLSCHAFT (DE) 1979-03-27 US claimed