Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28820897 | 1.00 | TSHR (0.50) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL87786 | 0.96 | TSHR (0.55) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL31485057 | 0.96 | TSHR (0.55) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL27707378 | 0.92 | TSHR (0.50) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL27981592 | 0.89 | TSHR (0.40) | TSHRTP53SRD5A2CA1CA2 | |
| Benzoic Acid SCHEMBL17797781 | 0.88 | TSHR (0.58) | TSHRTP53SRD5A2KMT2AALDH1A1 | |
| Benzoic Acid SCHEMBL532786 | 0.88 | TSHR (0.58) | TSHRTP53SRD5A2KMT2AALDH1A1 | |
| Terephthalic Acid SCHEMBL14657242 | 0.86 | USP2 (0.53) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL6442298 | 0.86 | KMT2A (0.55) | TSHRTP53SRD5A2KMT2A | |
| Ethylene Glycol SCHEMBL16245510 | 0.85 | DRD2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118256094-A | Polyester composite material and preparation method and application thereof | 广州合成材料研究院有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118240359-A | Polycarbonate composition and preparation method and application thereof | 金发科技股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118085516-A | Polyester material for cosmetic packaging container and preparation method thereof | 宁波杰立化妆品包装用品有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-116373418-A | Low-temperature gas barrier material and preparation method thereof | 江苏江华阀业有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-109676915-B | Wheel-shaped porous support and preparation method and application thereof | 复旦大学 | 2022-02-15 | — | — | CN | claimed |
| CN-113276512-A | Recyclable cooking bag and recyclable cooking polyester film thereof | 南亚塑胶工业股份有限公司 | 2021-08-20 | — | — | CN | claimed |
| CN-111469514-B | Three-layer co-pressing composite membrane special for invisible correction and preparation method thereof | 北京化工大学 | 2021-06-22 | — | — | CN | claimed |
| CN-111469514-A | Three-layer co-pressing composite membrane special for invisible correction and preparation method thereof | 北京化工大学 | 2020-07-31 | — | — | CN | claimed |
| CN-111439015-A | Double-layer coated PVC wood-plastic profile and preparation method thereof | 吉林庭然景观材料科技有限公司 | 2020-07-24 | — | — | CN | claimed |
| CN-118256094-A | Polyester composite material and preparation method and application thereof | 广州合成材料研究院有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-118256094-A | Polyester composite material and preparation method and application thereof | 广州合成材料研究院有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-118240359-A | Polycarbonate composition and preparation method and application thereof | 金发科技股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118240359-A | Polycarbonate composition and preparation method and application thereof | 金发科技股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118085516-A | Polyester material for cosmetic packaging container and preparation method thereof | 宁波杰立化妆品包装用品有限公司 | 2024-05-28 | — | — | CN | disclosed |
| US-7982380-B2 | Front filter for plasma display and plasma display | DAI NIPPON PRINTING CO., LTD. (JP) | 2011-07-19 | — | — | US | disclosed |
| US-20100177397-A1 | FRONT FILTER FOR PLASMA DISPLAY AND PLASMA DISPLAY | DAI NIPPON PRINTING CO., LTD. (JP) | 2010-07-15 | — | — | US | disclosed |
| US-20090246475-A1 | DECORATIVE FILM FOR MOLDING | DAI NIPPON PRINTING CO., LTD. | 2009-10-01 | — | — | US | disclosed |
| EP-2088176-A1 | Ink composition, inkjet recording method, printed material, and molded printed material | FUJIFILM Corporation (JP) | 2009-08-12 | — | — | EP | disclosed |
| CN-101503587-A | Ink composition, inkjet recording method, printed material, and molded printed material | FUJIFILM CORP (JP) | 2009-08-12 | — | — | CN | disclosed |
| US-5034458-A | Polycarbonate for use in molding materials for laminated films and for electronics | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-23 | — | — | US | disclosed |