Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3620374 | 0.91 | HSD11B1 (0.61) | ALDH1A1HSD11B1HPGDNPSR1EPHX2 | |
| SCHEMBL10132087 | 0.83 | HSD11B1 (0.69) | ALDH1A1HSD11B1HPGDNPSR1EPHX1 | |
| SCHEMBL9124247 | 0.82 | HPGD (0.56) | ALDH1A1HPGDNPSR1EPHX2EPHX1 | |
| SCHEMBL14748208 | 0.80 | HPGD (0.55) | ALDH1A1HPGDNPSR1EPHX2EPHX1 | |
| SCHEMBL2625524 | 0.80 | SMN1; SMN2 (0.55) | ALDH1A1HSD11B1HPGDNPSR1EPHX1 | |
| SCHEMBL12572628 | 0.78 | SMN1; SMN2 (0.53) | ALDH1A1HSD11B1HPGDNPSR1EPHX2 | |
| SCHEMBL13544829 | 0.77 | HSD11B1 (0.61) | ALDH1A1HSD11B1HPGDNPSR1EPHX2 | |
| SCHEMBL4958038 | 0.76 | HPGD (0.50) | ALDH1A1HPGDNPSR1EPHX2EPHX1 | |
| SCHEMBL11570602 | 0.76 | NPSR1 (0.59) | ALDH1A1HPGDNPSR1EPHX2EPHX1 | |
| SCHEMBL2625523 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1HSD11B1HPGDNPSR1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | disclosed |