Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13544829 | 0.92 | HSD11B1 (0.61) | HSD11B1SMN1; SMN2HPGDNPSR1KMT2A | |
| SCHEMBL3620374 | 0.92 | HSD11B1 (0.61) | HSD11B1SMN1; SMN2HPGDNPSR1KMT2A | |
| SCHEMBL21884192 | 0.90 | HSD11B1 (0.58) | HSD11B1SMN1; SMN2HPGDNPSR1KMT2A | |
| SCHEMBL23518575 | 0.86 | HSD11B1 (0.54) | HSD11B1SMN1; SMN2HPGDNPSR1KMT2A | |
| SCHEMBL23518502 | 0.86 | HSD11B1 (0.54) | HSD11B1SMN1; SMN2HPGDNPSR1KMT2A | |
| SCHEMBL1515374 | 0.86 | HSD11B1 (0.54) | HSD11B1SMN1; SMN2HPGDNPSR1KMT2A | |
| SCHEMBL5327904 | 0.83 | ALDH1A1 (0.56) | HSD11B1SMN1; SMN2HPGDNPSR1KMT2A | |
| SCHEMBL3623686 | 0.83 | HSD11B1 (1.00) | HSD11B1KMT2AEPHX1 | |
| SCHEMBL12478049 | 0.83 | HSD11B1 (0.51) | HSD11B1SMN1; SMN2HPGDNPSR1KMT2A | |
| SCHEMBL23518576 | 0.82 | HSD11B1 (0.51) | HSD11B1HPGDNPSR1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101186-B2 | Peptides that block the binding of IgG to FcRn | SYNTONIX PHARMACEUTICALS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-20070254831-A1 | PEPTIDES THAT BLOCK THE BINDING OF IgG to FcRn | BIOGEN HEMOPHILIA INC. | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254831-A1 | PEPTIDES THAT BLOCK THE BINDING OF IgG to FcRn | FCGRT, FCGR3B, FCGR1A | HSD11B1 3869/4885SMN1; SMN2 4722/4885HPGD 3932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.