Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.52 |
| ▸ | THRA | P10827 | 9/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891500 | 0.89 | THRA (0.65) | THRBTHRA | |
| SCHEMBL3229107 | 0.86 | THRB (0.52) | THRBTHRATDP1MAPTRORC | |
| SCHEMBL5324895 | 0.81 | THRB (0.54) | THRBTHRARORC | |
| SCHEMBL6268456 | 0.79 | NR1H4 (0.45) | THRBTHRATDP1NR1H4POLB | |
| SCHEMBL22959316 | 0.77 | NR1H4 (0.69) | THRBTHRANR1H4ALDH1A1 | |
| SCHEMBL26982543 | 0.77 | NR1H4 (0.50) | THRBTHRANR1H4POLBMAPT | |
| SCHEMBL8041378 | 0.76 | SMN1; SMN2 (0.51) | THRBTDP1POLBMAPTMAPK1 | |
| SCHEMBL3221689 | 0.76 | THRA (0.57) | THRBTHRA | |
| SCHEMBL5327698 | 0.76 | RORC (0.62) | THRBTHRAMAPTRORC | |
| SCHEMBL26982565 | 0.76 | NR1H4 (0.44) | THRBTHRATDP1NR1H4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | disclosed |