SCHEMBL5328080

SCHEMBL5328080

CCCc1nc(C(=O)O)c(C(C)(C)O)n1Cc1ccc(-c2ccccc2C#N)cc1

nearest known ligand 0.61

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.61
AGTR1 P30556 1/20 0.50
AGTR2 P50052 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4592079 0.89 PPARG (0.57) PPARGAGTR1AGTR2
SCHEMBL2578611 0.86 AGTR1 (0.67) PPARGAGTR1AGTR2
SCHEMBL12737295 0.82 PPARG (0.64) PPARGAGTR1AGTR2
SCHEMBL7430230 0.81 PPARG (0.63) PPARGAGTR1AGTR2
SCHEMBL668602 0.80 AGTR1 (0.55) AGTR1AGTR2
SCHEMBL987699 0.79 AGTR1 (0.57) PPARGAGTR1AGTR2
SCHEMBL1417546 0.79 AGTR1 (0.61) PPARGAGTR1AGTR2
Water SCHEMBL2576559 0.79 AGTR1 (0.63) AGTR1AGTR2
SCHEMBL8207617 0.79 PPARG (0.60) PPARGAGTR1
SCHEMBL12349095 0.79 PPARG (0.60) PPARGAGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007148344-A2 PROCESS FOR THE PREPARATION OF OLMESARTAN MEDOXOMIL MATRIX LABORATORIES LIMITED (IN) 2007-12-27 WO disclosed