Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.63 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12737295 | 0.89 | PPARG (0.64) | PPARGAGTR1AGTR2 | |
| SCHEMBL2578611 | 0.86 | AGTR1 (0.67) | PPARGAGTR1AGTR2 | |
| SCHEMBL987699 | 0.83 | AGTR1 (0.57) | PPARGAGTR1AGTR2 | |
| SCHEMBL5328080 | 0.81 | PPARG (0.61) | PPARGAGTR1AGTR2 | |
| SCHEMBL4010668 | 0.80 | PPARG (0.63) | PPARGAGTR1 | |
| SCHEMBL17031409 | 0.79 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL4012581 | 0.79 | PPARG (0.59) | PPARGAGTR1AGTR2 | |
| SCHEMBL4011358 | 0.79 | PPARG (0.61) | PPARGAGTR1 | |
| SCHEMBL4013891 | 0.79 | PPARG (0.61) | PPARGAGTR1AGTR2 | |
| SCHEMBL214 | 0.79 | PPARG (0.56) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503785-B1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2001-04-25 | — | — | EP | disclosed |