Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328239 | 0.85 | ACACB (0.42) | ACACBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5327174 | 0.82 | ALDH1A1 (0.51) | ACACBALDH1A1DNMT3AMEN1KMT2A | |
| SCHEMBL5325174 | 0.81 | ALDH1A1 (0.70) | ACACBALDH1A1DNMT3AL3MBTL1PSMB5 | |
| SCHEMBL5326665 | 0.81 | NR1H4 (0.55) | ACACBALDH1A1SMN1; SMN2DNMT3AMEN1 | |
| SCHEMBL5325179 | 0.81 | NR1H4 (0.55) | ACACBALDH1A1SMN1; SMN2DNMT3AMEN1 | |
| SCHEMBL5324896 | 0.81 | NR1H4 (0.55) | ACACBALDH1A1SMN1; SMN2DNMT3AMEN1 | |
| SCHEMBL14398212 | 0.79 | ALDH1A1 (0.48) | ACACBALDH1A1SMN1; SMN2DNMT3AMEN1 | |
| SCHEMBL14397665 | 0.79 | KMT2A (0.60) | ACACBALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL5324806 | 0.77 | ALDH1A1 (0.48) | ACACBALDH1A1SMN1; SMN2DNMT3AMEN1 | |
| SCHEMBL14399342 | 0.76 | ALDH1A1 (0.52) | ACACBALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | claimed |
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |