Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332287 | 0.90 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD11B1POLBHTT | |
| SCHEMBL5331220 | 0.86 | HSD11B1 (0.53) | ALDH1A1HPGDHSD11B1HTTTSHR | |
| SCHEMBL5966689 | 0.82 | TRPV1 (0.59) | ALDH1A1HPGDHSD11B1POLBHTT | |
| SCHEMBL8947294 | 0.81 | MAPK1 (0.61) | ALDH1A1HPGDHSD11B1POLBHTT | |
| SCHEMBL8947310 | 0.80 | TRPV1 (0.63) | ALDH1A1HPGDHSD11B1POLBHTT | |
| SCHEMBL8947249 | 0.79 | MEN1 (0.59) | ALDH1A1HPGDHSD11B1POLBHTT | |
| SCHEMBL5966693 | 0.77 | ALDH1A1 (0.74) | ALDH1A1HPGDHSD11B1POLBHTT | |
| SCHEMBL9568925 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD11B1POLBHTT | |
| SCHEMBL5966710 | 0.76 | CYP1A2 (0.59) | ALDH1A1HPGDHSD11B1POLBHTT | |
| SCHEMBL408079 | 0.75 | HSD11B1 (0.56) | ALDH1A1HPGDHSD11B1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | ALDH1A1 2972/4885HPGD 1825/4885HSD11B1 4746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.