Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29054492 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KMT2ACYP3A4MEN1SMN1; SMN2 | |
| SCHEMBL13805308 | 0.87 | ALDH1A1 (1.00) | ALDH1A1KMT2ACYP3A4CYP2C9MEN1 | |
| SCHEMBL597374 | 0.85 | ALDH1A1 (0.63) | ALDH1A1KMT2ACYP3A4CYP2C9MEN1 | |
| SCHEMBL11883814 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KMT2ACYP3A4CYP2C9MEN1 | |
| SCHEMBL3664055 | 0.84 | MAPT (0.54) | ALDH1A1KMT2ACYP3A4MEN1SMN1; SMN2 | |
| SCHEMBL9149245 | 0.79 | ALDH1A1 (0.68) | ALDH1A1KMT2ACYP3A4MEN1POLB | |
| SCHEMBL22939099 | 0.78 | ALDH1A1 (0.71) | ALDH1A1KMT2ACYP3A4CYP2C9MEN1 | |
| SCHEMBL22939100 | 0.78 | ALDH1A1 (0.71) | ALDH1A1KMT2ACYP3A4CYP2C9MEN1 | |
| SCHEMBL6055735 | 0.78 | MAPT (0.54) | ALDH1A1KMT2ACYP3A4MEN1AKR1C3 | |
| SCHEMBL11550449 | 0.76 | ALDH1A1 (0.73) | ALDH1A1KMT2ACYP3A4CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419966-B1 | UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF | ALCON INC (CH) | 2020-03-25 | — | — | EP | disclosed |
| US-7294724-B2 | Process for manufacture of fluoran dyes | APPLETON PAPERS INC. (US) | 2007-11-13 | — | — | US | disclosed |
| WO-2007021635-A2 | PROCESS FOR MANUFACTURE OF FLUORAN DYES | APPLETON PAPERS INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070037989-A1 | Reacting in the presence of an alkane- or arenesulfonic acid a (m-hydrocarboxyphenyl)(p-disubstitutedaminophenyl)amine and an o-benzoylbenzoic acid to form a fluoran dye, e.g., 2',3'-dimethyl-6'-[4-dimethylaminophenyl]amino-spiro[isobenzofuran-1(3H), 9'-[9H]xanthene]-3-one | APPLETON PAPER INC. (US) | 2007-02-15 | — | — | US | disclosed |
| US-4954631-A | INFRARED ABSORPTION; BLACK | SHIN NISSO KAKO CO., LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| US-4826806-A | CHROMOGENIC DYES | SHIN NISSO KAKO CO., LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037989-A1 | Reacting in the presence of an alkane- or arenesulfonic acid a (m-hydrocarboxyphenyl)(p-disubstitutedaminophenyl)amine and an o-benzoylbenzoic acid to form a fluoran dye, e.g., 2',3'-dimethyl-6'-[4-dimethylaminophenyl]amino-spiro[isobenzofuran-1(3H), 9'-[9H]xanthene]-3-one | ARSA, AHR, C9 | ALDH1A1 183/4885KMT2A 2266/4885CYP3A4 1899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.