Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22939100 | 0.85 | ALDH1A1 (0.71) | ALDH1A1POLBNR4A1KMT2AMEN1 | |
| SCHEMBL22939099 | 0.85 | ALDH1A1 (0.71) | ALDH1A1POLBNR4A1KMT2AMEN1 | |
| SCHEMBL5328376 | 0.85 | ALDH1A1 (0.77) | ALDH1A1POLBNR4A1KMT2AMEN1 | |
| SCHEMBL8649520 | 0.82 | KMT2A (0.58) | ALDH1A1HSP90AA1KMT2AMEN1L3MBTL1 | |
| SCHEMBL2674156 | 0.82 | CDC25A (0.47) | ALDH1A1HSP90AA1POLBNR4A1SMN1; SMN2 | |
| SCHEMBL2673025 | 0.82 | KDM4E (0.54) | ALDH1A1HSP90AA1POLBNR4A1SMN1; SMN2 | |
| SCHEMBL31336107 | 0.81 | CA1 (0.54) | ALDH1A1HSP90AA1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL383516 | 0.81 | CA1 (0.54) | ALDH1A1HSP90AA1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL22939024 | 0.79 | ALDH1A1 (0.63) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9450719 | 0.79 | CA1 (0.70) | ALDH1A1NR4A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10684294-B2 | Diarylether-based fluorogenic probes for detection of hypochlorous acid or hydroxyl radical | THE UNIVERSITY OF HONG KONG (HK) | 2020-06-16 | — | — | US | disclosed |
| EP-3431480-A1 | DIARYLAMINE-BASED FLUOROGENIC PROBES FOR DETECTION OF PEROXYNITRITE | The University Of Hong Kong (CN) | 2019-01-23 | — | — | EP | disclosed |
| US-9651528-B2 | Diarylamine-based fluorogenic probes for detection of peroxynitrite | THE UNIVERSITY OF HONG KONG (CN) | 2017-05-16 | — | — | US | disclosed |
| US-9651528-B2 | Diarylamine-based fluorogenic probes for detection of peroxynitrite | THE UNIVERSITY OF HONG KONG (CN) | 2017-05-16 | — | — | US | disclosed |
| US-20160312033-A1 | DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL | VERSITECH LIMITED (HK) | 2016-10-27 | — | — | US | disclosed |
| US-20160312033-A1 | DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL | VERSITECH LIMITED (HK) | 2016-10-27 | — | — | US | disclosed |
| WO-2013113279-A1 | DIARYLAMINE-BASED FLUOROGENIC PROBES FOR DETECTION OF PEROXYNITRITE | THE UNIVERSITY OF HONG KONG (CN) | 2013-08-08 | — | — | WO | disclosed |
| US-20130196362-A1 | DIARYLAMINE-BASED FLUOROGENIC PROBES FOR DETECTION OF PEROXYNITRITE | THE UNIVERSITY OF HONG KONG (CN) | 2013-08-01 | — | — | US | disclosed |
| US-20130196362-A1 | DIARYLAMINE-BASED FLUOROGENIC PROBES FOR DETECTION OF PEROXYNITRITE | THE UNIVERSITY OF HONG KONG (CN) | 2013-08-01 | — | — | US | disclosed |
| US-8114904-B2 | Luminescence quenchers and fluorogenic probes for detection of reactive species | Versitech Limited & Morningside Ventures Limited (CN) | 2012-02-14 | — | — | US | disclosed |
| US-7399639-B2 | Sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-07-15 | — | — | US | disclosed |
| US-7399639-B2 | Sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-07-15 | — | — | US | disclosed |
| US-7160732-B2 | Fluorescein-based metal sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160732-B2 | Fluorescein-based metal sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-01-09 | — | — | US | disclosed |
| US-7018840-B2 | Ligand for in the detection of toxic metals in mammals | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-03-28 | — | — | US | disclosed |
| US-20040224420-A1 | Sensors, and methods of making and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-11-11 | — | — | US | disclosed |
| US-20030068275-A1 | Coordination complexes for detecting analytes, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2003-04-10 | — | — | US | disclosed |
| US-20030008405-A1 | Fluorescent metal sensors, and methods of making and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-09 | — | — | US | disclosed |
| US-20020106697-A1 | Fluorescein-based metal sensors, and methods of making and using the same | MASSACHUSETTS INSTIUTE OF TECHOLOGY | 2002-08-08 | — | — | US | disclosed |
| WO-2002004562-A2 | FLUORESCEIN-BASED METAL SENSORS, AND METHODS OF MAKING AND USING THE SAME | MASSACHUSSETS INSTITUTE OF TECHNOLOGY (US) | 2002-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030068275-A1 | Coordination complexes for detecting analytes, and methods of making and using the same | SPR, CACYBP, CA13 | ALDH1A1 2403/4885HSP90AA1 4697/4885POLB 535/4885 |
| US-20020106697-A1 | Fluorescein-based metal sensors, and methods of making and using the same | SLC30A5, SLC30A6, SLC39A14 | ALDH1A1 1255/4885HSP90AA1 3758/4885POLB 4448/4885 |
| US-20160312033-A1 | DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL | HAGH, HADH, FECH | ALDH1A1 334/4885HSP90AA1 1499/4885POLB 2612/4885 |
| US-10684294-B2 | Diarylether-based fluorogenic probes for detection of hypochlorous acid or hydroxyl radical | HAGH, HADH, FECH | ALDH1A1 334/4885HSP90AA1 1499/4885POLB 2612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.