Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PANK1 | Q8TE04 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329533 | 0.87 | CYP3A4 (0.36) | KMT2ABRD4RAB9ATP53CYP3A4 | |
| SCHEMBL5327618 | 0.85 | GLA (0.38) | KMT2ARAB9ACYP3A4CYP2D6CYP2C9 | |
| Bicarbonate SCHEMBL5984921 | 0.84 | GLA (0.37) | KMT2ARAB9ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5327517 | 0.83 | MCHR1 (0.41) | BRD4RAB9ANPC1 | |
| SCHEMBL5449403 | 0.83 | MCHR1 (0.41) | BRD4RAB9ANPC1 | |
| SCHEMBL5327514 | 0.83 | MCHR1 (0.41) | BRD4RAB9ANPC1 | |
| SCHEMBL5559185 | 0.82 | KMT2A (0.42) | ADRA1AKMT2ARAB9ATP53 | |
| SCHEMBL4994479 | 0.81 | KMT2A (0.36) | KMT2ARAB9ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5330704 | 0.81 | SMN1; SMN2 (0.43) | KMT2ARAB9ATP53CYP2C9NPC1 | |
| Bicarbonate SCHEMBL4976269 | 0.81 | KMT2A (0.35) | KMT2ARAB9ACYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141253-A1 | PROCESS FOR THE PRODUCTION OF INTERMEDIATES FOR THE PREPARATION OF TRICYCLIC IMIDAZOPYRIDINES | NYCOMED GMBH (DE) | 2007-12-13 | — | — | WO | disclosed |