Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 6/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327514 | 1.00 | MCHR1 (0.41) | MCHR1CXCR2BRD4TTKRAB9A | |
| SCHEMBL5327517 | 1.00 | MCHR1 (0.41) | MCHR1CXCR2BRD4TTKRAB9A | |
| SCHEMBL5569980 | 0.88 | LMNA (0.38) | CXCR2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL5569978 | 0.88 | LMNA (0.38) | CXCR2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL4977670 | 0.85 | P2RX3 (0.36) | RAB9ANPC1KDM4EMAPT | |
| SCHEMBL5328503 | 0.83 | ADRA1D (0.40) | BRD4RAB9ANPC1 | |
| SCHEMBL4977432 | 0.82 | PRKDC (0.34) | CXCR2RAB9ANPC1MAPT | |
| SCHEMBL5451120 | 0.82 | PRKDC (0.34) | CXCR2RAB9ANPC1MAPT | |
| SCHEMBL5566372 | 0.82 | PRKDC (0.34) | CXCR2RAB9ANPC1MAPT | |
| SCHEMBL5566461 | 0.81 | KMT2A (0.39) | CXCR2RAB9ANPC1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141253-A1 | PROCESS FOR THE PRODUCTION OF INTERMEDIATES FOR THE PREPARATION OF TRICYCLIC IMIDAZOPYRIDINES | NYCOMED GMBH (DE) | 2007-12-13 | — | — | WO | disclosed |