SCHEMBL532852

SCHEMBL532852

COc1cc(C(Cl)(Cl)Cl)ccc1-c1ncncn1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 13/20 0.36
ALOX5AP P20292 1/20 0.36
FEN1 P39748 1/20 0.36
CYP3A4 P08684 1/20 0.35
CYP17A1 P05093 4/20 0.34
CRHR1 P34998 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15464143 0.77 CCNT1 (0.45) SCN9A
SCHEMBL607282 0.77 TSHR (0.35)
SCHEMBL28036711 0.77 CYP1A1 (0.51) CYP3A4CRHR1
Ammonia Solution, Strong SCHEMBL19740971 0.76 CCNT1 (0.44) SCN9A
SCHEMBL7107019 0.74 CRHR1 (0.31) CRHR1
SCHEMBL1082436 0.72 TSHR (0.32)
SCHEMBL174453 0.71 CYP1A2 (0.54) CYP3A4
SCHEMBL11216591 0.67 IDO1 (0.47) CYP3A4
SCHEMBL29848197 0.67 IDO1 (0.47) CYP3A4
SCHEMBL20210912 0.65 SCN9A (0.48) SCN9AALOX5APFEN1CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3132932-B1 LITHOGRAPHIC IMAGING AND PRINTING WITH NEGATIVE-WORKING PHOTORESPONSIVE PRINTING MEMBERS PRESSTEK LLC (US) 2020-04-15 EP disclosed
US-20180117900-A1 EDGE TREATMENT FOR DEVELOP-ON-PRESS LITHOGRAPHIC PRINTING MEMBERS PRESSTEK, INC. 2018-05-03 US disclosed
EP-3132932-A2 LITHOGRAPHIC IMAGING AND PRINTING WITH NEGATIVE-WORKING PHOTORESPONSIVE PRINTING MEMBERS Presstek, LLC. (US) 2017-02-22 EP disclosed
US-20170021656-A1 LITHOGRAPHIC IMAGING AND PRINTING WITH NEGATIVE-WORKING PHOTORESPONSIVE PRINTING MEMBERS PRESSTEK, LLC. 2017-01-26 US disclosed
EP-2033051-B1 NEGATIVE-WORKING IMAGEABLE ELEMENTS EASTMAN KODAK CO (US) 2016-11-30 EP disclosed
EP-2217970-B1 IMAGEABLE ELEMENTS WITH COMPONENTS HAVING 1H-TETRAZOLE GROUPS EASTMAN KODAK CO (US) 2015-06-03 EP disclosed
CN-101884014-B Imageable elements with components having 1h-tetrazole groups EASTMAN KODAK CO 2013-09-18 CN disclosed
CN-101971095-B Negative-working imageable elements with improved abrasion resistance EASTMAN KODAK CO 2013-09-04 CN disclosed
US-20120231394-A1 IMAGEABLE ELEMENTS WITH COLORANTS QUALEX INC. 2012-09-13 US disclosed
CN-101548239-B Negative-working radiation-sensitive compositions and imageable materials EASTMAN KODAK CO 2012-07-04 CN disclosed
WO-2008073223-A2 NEGATIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS AND IMAGEABLE MATERIALS EASTMAN KODAK COMPANY (US) 2008-06-19 WO disclosed
US-20080138741-A1 NEGATIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS AND IMAGEABLE MATERIALS BANK OF AMERICA, N.A., AS AGENT 2008-06-12 US disclosed
US-20080085475-A1 METHOD OF IMAGING AND DEVELOPING NEGATIVE-WORKING ELEMENTS TAO TING 2008-04-10 US disclosed
WO-2008036170-A1 NEGATIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS AND IMAGEABLE MATERIALS EASTMAN KODAK COMPANY (US) 2008-03-27 WO disclosed
US-20080070152-A1 NEGATIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS AND IMAGEABLE MATERIALS BANK OF AMERICA, N.A., AS AGENT 2008-03-20 US disclosed
WO-2008027227-A1 METHOD OF IMAGING AND DEVELOPING NEGATIVE-WORKING ELEMENTS EASTMAN KODAK COMPANY (US) 2008-03-06 WO disclosed
US-7326521-B1 Method of imaging and developing negative-working elements EASTMAN KODAK COMPANY (US) 2008-02-05 US disclosed
US-20080008957-A1 Negative-working radiation-sensitive compositions and imageable elements EASTMAN KODAK COMPANY 2008-01-10 US disclosed
WO-2008002393-A2 NEGATIVE-WORKING RADIATION-SENSITIVE COMPOSITIONS AND IMAGEABLE ELEMENT EASTMAN KODAK COMPANY (US) 2008-01-03 WO disclosed
US-7175969-B1 Method of preparing negative-working radiation-sensitive elements EASTMAN KODAK COMPANY (US) 2007-02-13 US disclosed