SCHEMBL607282

SCHEMBL607282

ClC(Cl)(Cl)c1ccc(-c2ncncn2)c(C(Cl)(Cl)Cl)c1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1082436 0.83 TSHR (0.32) TSHR
SCHEMBL532852 0.77 SCN9A (0.36)
SCHEMBL3011353 0.75 DGAT1 (0.39) TSHR
SCHEMBL195523 0.73 TSHR (0.32) TSHR
SCHEMBL491074 0.70 TSHR (0.32) TSHR
SCHEMBL7870951 0.68 TSHR (0.44) TSHR
SCHEMBL2985784 0.68
SCHEMBL7107019 0.66 CRHR1 (0.31)
SCHEMBL3628549 0.64 CYP2A6 (0.32)
SCHEMBL21578108 0.63 HSP90AA1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8113116-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-02-14 US disclosed
US-20070214987-A1 Lithographic printing plate precursor FUJIFILM CORPORATION 2007-09-20 US disclosed