Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336949 | 0.81 | ALDH1A1 (0.65) | MEN1KMT2ACYP3A4CYP2C9LMNA | |
| SCHEMBL14542397 | 0.80 | TP53 (0.62) | MEN1KMT2ACYP3A4CYP2C9LMNA | |
| SCHEMBL6408915 | 0.75 | ALDH1A1 (0.57) | MEN1KMT2ACYP3A4CYP2C9LMNA | |
| SCHEMBL5333033 | 0.74 | ALDH1A1 (0.75) | MEN1KMT2AMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL22404682 | 0.74 | CYP3A4 (0.58) | MEN1KMT2ACYP3A4CYP2C9LMNA | |
| SCHEMBL4210904 | 0.73 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1ALOX15HSD17B10 | |
| SCHEMBL20936265 | 0.73 | ALDH1A1 (0.70) | MEN1KMT2ACYP3A4CYP2C9LMNA | |
| SCHEMBL21045566 | 0.73 | ALDH1A1 (0.68) | MEN1KMT2ACYP3A4CYP2C9LMNA | |
| SCHEMBL5411609 | 0.73 | MEN1 (0.86) | MEN1KMT2ACYP3A4CYP2C9LMNA | |
| SCHEMBL5330329 | 0.73 | KMT2A (0.86) | MEN1KMT2ACYP3A4CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |