Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CDC25A | P30304 | 1/20 | 0.57 |
| ▸ | CDC25B | P30305 | 1/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332252 | 0.84 | POLB (0.68) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL5330386 | 0.79 | TP53 (0.67) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL5330392 | 0.79 | TP53 (0.67) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL5334182 | 0.79 | PKM (0.89) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL5329760 | 0.78 | MEN1 (0.84) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5411609 | 0.76 | MEN1 (0.86) | ALDH1A1MEN1KMT2AL3MBTL1CDC25A | |
| SCHEMBL5330329 | 0.76 | KMT2A (0.86) | ALDH1A1MEN1KMT2ACDC25ACDC25B | |
| SCHEMBL27787548 | 0.75 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL5328529 | 0.74 | MEN1 (0.70) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL12262621 | 0.73 | PKM (0.80) | ALDH1A1MEN1KMT2AL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |