Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 13/20 | 0.38 |
| ▸ | SLC8A1 | P32418 | 2/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | ATP4A | P20648 | 1/20 | 0.31 |
| ▸ | ATP4B | P51164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569799 | 0.84 | CYP3A4 (0.33) | RIPK1SLC8A1CYP3A4CYP2C9ATP4A | |
| SCHEMBL5566402 | 0.84 | CYP3A4 (0.33) | RIPK1SLC8A1CYP3A4CYP2C9ATP4A | |
| SCHEMBL5571355 | 0.84 | CYP3A4 (0.33) | RIPK1SLC8A1CYP3A4CYP2C9ATP4A | |
| SCHEMBL5569811 | 0.77 | RIPK1 (0.41) | RIPK1CYP3A4CYP2C9ATP4AATP4B | |
| SCHEMBL5570783 | 0.77 | RIPK1 (0.41) | RIPK1CYP3A4CYP2C9ATP4AATP4B | |
| SCHEMBL5422396 | 0.76 | ATP4A (0.42) | RIPK1SLC8A1SPRHCRTR1HCRTR2 | |
| SCHEMBL5417817 | 0.75 | ATP4A (0.46) | RIPK1SLC8A1CYP3A4CYP2C9ATP4A | |
| SCHEMBL5989112 | 0.75 | ATP4A (0.46) | RIPK1SLC8A1CYP3A4CYP2C9ATP4A | |
| SCHEMBL5328763 | 0.75 | GBA1 (0.31) | SPR | |
| SCHEMBL5414016 | 0.75 | ATP4A (0.41) | SLC8A1SPRCYP3A4CYP2C9ATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141253-A1 | PROCESS FOR THE PRODUCTION OF INTERMEDIATES FOR THE PREPARATION OF TRICYCLIC IMIDAZOPYRIDINES | NYCOMED GMBH (DE) | 2007-12-13 | — | — | WO | claimed |
| WO-2007141253-A1 | PROCESS FOR THE PRODUCTION OF INTERMEDIATES FOR THE PREPARATION OF TRICYCLIC IMIDAZOPYRIDINES | NYCOMED GMBH (DE) | 2007-12-13 | — | — | WO | disclosed |