Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28243319 | 0.87 | ALDH1A1 (0.50) | ARGAAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL3317596 | 0.80 | CYP3A4 (0.49) | GAAALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL523138 | 0.77 | SMN1; SMN2 (0.62) | ARGAAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL5326209 | 0.76 | ALDH1A1 (0.50) | ARGAAALDH1A1POLBCYP3A4 | |
| SCHEMBL5323737 | 0.76 | CYP1A2 (0.45) | ARALDH1A1POLBSMN1; SMN2CYP1A2 | |
| SCHEMBL21295558 | 0.76 | CYP3A4 (0.49) | GAAALDH1A1POLBSMN1; SMN2CYP1A2 | |
| SCHEMBL20262023 | 0.76 | CYP1A2 (0.45) | GAAALDH1A1POLBSMN1; SMN2CYP1A2 | |
| SCHEMBL1335043 | 0.73 | ALDH1A1 (0.49) | ARGAAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1334294 | 0.73 | ALDH1A1 (0.49) | ARGAAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL3251180 | 0.73 | POLB (0.53) | ARGAAALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |