Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328808 | 0.89 | FTO (0.51) | FTOHTTMAPTHPGDMEN1 | |
| SCHEMBL6248294 | 0.88 | FTO (0.53) | FTOHTTMAPTHPGDMEN1 | |
| SCHEMBL5497268 | 0.81 | FTO (0.48) | FTOHTTMAPTHPGDMEN1 | |
| SCHEMBL8647706 | 0.81 | FTO (0.48) | FTOHTTMAPTHPGDMEN1 | |
| SCHEMBL7621360 | 0.81 | FTO (0.48) | FTOHTTMAPTHPGDMEN1 | |
| SCHEMBL2105358 | 0.81 | FTO (0.48) | FTOHTTMAPTHPGDMEN1 | |
| SCHEMBL384698 | 0.81 | FTO (0.54) | FTOHTTMAPTHPGDMEN1 | |
| SCHEMBL887742 | 0.80 | FTO (0.49) | FTOHTTMAPTHPGDMEN1 | |
| SCHEMBL6037012 | 0.79 | ALDH1A1 (0.56) | FTOHTTMAPTHPGDMEN1 | |
| SCHEMBL2409136 | 0.79 | FTO (0.55) | FTOHTTMAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11085065-B2 | Phenotypic engineering of spores | Rotman, M. Boris (US) | 2021-08-10 | — | — | US | claimed |
| US-20170292143-A1 | Phenotypic engineering of spores | SUSSMAN, Daniel J. | 2017-10-12 | — | — | US | claimed |
| US-11085065-B2 | Phenotypic engineering of spores | Rotman, M. Boris (US) | 2021-08-10 | — | — | US | disclosed |
| US-20170292143-A1 | Phenotypic engineering of spores | SUSSMAN, Daniel J. | 2017-10-12 | — | — | US | disclosed |
| WO-2007139601-A2 | PHENOTYPIC ENGINEERING OF SPORE | BCR DIAGNOSTICS, INC. (US) | 2007-12-06 | — | — | WO | disclosed |
| US-20070238145-A1 | Phenotypic engineering of spores | BCR DIAGNOSTICS, INC. | 2007-10-11 | — | — | US | disclosed |