SCHEMBL384698

SCHEMBL384698

CC(=O)c1ccc2c(c1C(C)=O)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.54
MAPT P10636 4/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
HPGD P15428 2/20 0.54
HTT P42858 2/20 0.54
CYP2C19 P33261 1/20 0.54
RECQL P46063 1/20 0.54
BLM P54132 1/20 0.54
SMAD3 P84022 1/20 0.54
PRMT1 Q99873 1/20 0.54
ACE2 Q9BYF1 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALDH1A1 P00352 2/20 0.52
ALOX12 P18054 2/20 0.52
CYP2C9 P11712 1/20 0.52
ALOX15 P16050 1/20 0.52
BRCA1 P38398 1/20 0.52
HSD17B10 Q99714 1/20 0.52
LMNA P02545 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2407192 0.86 FTO (0.59) FTOMAPTMEN1KMT2AHPGD
SCHEMBL2342544 0.86 FTO (0.50) FTOMAPTMEN1KMT2AHPGD
SCHEMBL4802179 0.86 HPGD (0.51) FTOMAPTMEN1KMT2AHPGD
SCHEMBL6037012 0.84 ALDH1A1 (0.56) FTOMAPTMEN1KMT2AHPGD
SCHEMBL9633780 0.84 DHFR (0.39) FTOMAPTMEN1KMT2AHPGD
SCHEMBL2407742 0.82 HPGD (0.52) FTOMAPTMEN1KMT2AHPGD
SCHEMBL5328808 0.82 FTO (0.51) FTOMAPTMEN1KMT2AHPGD
SCHEMBL7907421 0.81 ALDH1A1 (0.53) FTOMAPTMEN1KMT2AHPGD
SCHEMBL5328577 0.81 FTO (0.49) FTOMAPTMEN1KMT2AHPGD
SCHEMBL2989053 0.81 HPGD (0.53) FTOMAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 608 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117665177-A Method for detecting sodium fluorescein related substances 广西梧州制药(集团)股份有限公司 2024-03-08 CN claimed
CN-117285500-A Preparation method of high-purity sodium fluorescein 广西梧州制药(集团)股份有限公司 2023-12-26 CN claimed
WO-2023037158-A1 PROCESS FOR PREPARATION OF CRYSTALLINE FLUORESCEIN SODIUM FROM DIACETYLFLUORESCEIN OR FLUORESCEIN MACSEN DRUGS (IN) 2023-03-16 WO claimed
CN-113461651-A Purification method of high-purity fluorescein 山东绅联药业有限公司 2021-10-01 CN claimed
US-11085065-B2 Phenotypic engineering of spores Rotman, M. Boris (US) 2021-08-10 US claimed
CN-110004056-B Cell quantity and cell activity detection method and detection cavity device for tissue engineering reactor 北京航空航天大学 2020-12-11 CN claimed
CN-109609583-A Embryo's colouring method, the method and kit for judging Embryo viability 北京农学院 2019-04-12 CN claimed
US-20170292143-A1 Phenotypic engineering of spores SUSSMAN, Daniel J. 2017-10-12 US claimed
EP-3206723-A1 BIOLOGICAL INDICATOR American Sterilizer Company (US) 2017-08-23 EP claimed
US-9701968-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2017-07-11 US claimed
WO-2008079469-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-03 WO claimed
WO-2008073764-A2 SUBSTANTIALLY PURE FLUORESCEIN ALCON RESEARCH, LTD. (US) 2008-06-19 WO claimed
US-20080070231-A1 Reporter genes taken up by microorganism, and repressor gene inhibits expression AMERICAN STERILIZER COMPANY 2008-03-20 US claimed
US-20080070272-A1 STERILIZATION INDICATOR AMERICAN STERILIZER COMPANY 2008-03-20 US claimed
US-20030060441-A1 Nucleic acid triggered catalytic drug and probe release TAYLOR JOHN-STEPHEN (US) 2003-03-27 US claimed
EP-0371682-B1 Rapid method for determining efficacy of a sterilization cycle and rapid read-out biological indicator MINNESOTA MINING & MFG (US) 1996-05-22 EP claimed
US-5073488-A Using active enzyme MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-17 US claimed
EP-0371682-A2 Rapid method for determining efficacy of a sterilization cycle and rapid read-out biological indicator MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-06-06 EP claimed
EP-0215066-A1 VIABLE MICROORGANISM DETECTION BY INDUCED FLUORESCENCE UNIVERSITY OF CINCINNATI (US) 1987-03-25 EP claimed
WO-1986005206-A1 VIABLE MICROORGANISM DETECTION BY INDUCED FLUORESCENCE UNIVERSITY OF CINCINNATI (US) 1986-09-12 WO claimed