Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.60 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261601 | 0.82 | MAOB (0.78) | MAOBKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL4926069 | 0.80 | CLK1 (0.64) | MAOBKMT2AMEN1TAS1R3TAS1R1 | |
| SCHEMBL4927411 | 0.78 | MEN1 (0.77) | MAOBKMT2AMEN1TAS1R3TAS1R1 | |
| SCHEMBL8759043 | 0.76 | HPGD (0.70) | KMT2AMEN1TAS1R3TAS1R1MAPT | |
| SCHEMBL7000901 | 0.76 | MAOB (0.72) | MAOBKMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL4916970 | 0.76 | HPGDS (0.65) | KMT2AMEN1TAS1R3TAS1R1TP53 | |
| SCHEMBL4202984 | 0.75 | TAS1R3 (1.00) | TAS1R3TAS1R1MAPTTP53RXFP1 | |
| SCHEMBL20449479 | 0.75 | MAOB (0.59) | MAOBKMT2AMEN1TAS1R3TAS1R1 | |
| SCHEMBL6952697 | 0.75 | MAPT (0.48) | MAOBKMT2AMEN1MAPTTP53 | |
| SCHEMBL701161 | 0.74 | MAPT (0.54) | MAOBKMT2AMEN1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |
| WO-2007138112-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | disclosed |