Sugi Predict

Sugi Predict / Compounds / Eperezolid

Eperezolid

Eperezolid

SCHEMBL5328753

CC(=O)NC[C@H]1CN(c2ccc(N3CCN(C(=O)CO)CC3)c(F)c2)C(=O)O1.O=[PH](O)O.O=[PH](O)O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 8/20 0.71
▸ MAOB P27338 6/20 0.71
▸ MAOA P21397 5/20 0.71
▸ PTGS1 P23219 2/20 0.71
▸ SDHA P31040 2/20 0.71
▸ LMNA P02545 1/20 0.71
▸ CALML3 P27482 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eperezolid SCHEMBL186562 0.96 MAOB (0.76) F10MAOBMAOAPTGS1SDHA
Eperezolid SCHEMBL1176950 0.96 MAOB (0.76) F10MAOBMAOAPTGS1SDHA
Eperezolid SCHEMBL29421647 0.96 MAOB (0.76) F10MAOBMAOAPTGS1SDHA
Eperezolid SCHEMBL5325217 0.96 MAOB (0.75) F10MAOBMAOAPTGS1SDHA
Eperezolid SCHEMBL7497950 0.92 MAOB (0.85) F10MAOBMAOAPTGS1SDHA
SCHEMBL6160239 0.90 F10 (0.72) F10MAOBMAOAPTGS1SDHA
SCHEMBL6160243 0.90 F10 (0.72) F10MAOBMAOAPTGS1SDHA
SCHEMBL4163039 0.90 MAOA (0.67) F10MAOBMAOAPTGS1SDHA
SCHEMBL10151505 0.89 MAOB (0.76) F10MAOBMAOAPTGS1SDHA
SCHEMBL12674054 0.89 MAOB (0.73) F10MAOBMAOAPTGS1SDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007138381-A2 PHOSPHONATED OXAZOLIDINONES AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS TARGANTA THERAPEUTICS INC. (CA) 2007-12-06 — — WO disclosed