Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2623144 | 0.82 | TK1 (0.47) | PIM1 | |
| SCHEMBL28004905 | 0.79 | POLA1 (0.44) | GAAHTTTAAR1 | |
| SCHEMBL1286951 | 0.75 | — | — | |
| SCHEMBL3941170 | 0.68 | ACHE (0.40) | PIM1PIM2GAAKDM4EALDH1A1 | |
| SCHEMBL1992700 | 0.68 | PARP1 (0.41) | GAAKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL10518128 | 0.68 | ALDH1A1 (0.53) | GAAKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL30289849 | 0.68 | KDM4E (0.74) | GAAKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL19690815 | 0.68 | POLA1 (0.48) | HTT | |
| SCHEMBL24700878 | 0.68 | MAPT (0.40) | HTTHSD17B10SMN1; SMN2 | |
| SCHEMBL23139612 | 0.68 | NPSR1 (0.38) | HTTHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016450-A2 | METHODS FOR TREATING OR PREVENTING REACTIVATION OF A LATENT HERPESVIRUS INFECTION | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2007-02-08 | — | — | WO | disclosed |