Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 8/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.33 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5167134 | 0.78 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10LPAR3LPAR2 | |
| SCHEMBL10378936 | 0.78 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10PGRCHRM2 | |
| SCHEMBL14019302 | 0.76 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10PGRCHRM2 | |
| SCHEMBL7620877 | 0.75 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10PGRCHRM2 | |
| SCHEMBL13301617 | 0.73 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10PGRCHRM2 | |
| SCHEMBL16075571 | 0.73 | PLA2G2A (0.37) | ALDH1A1LMNAHSD17B10PGRCHRM2 | |
| SCHEMBL322669 | 0.73 | — | — | |
| SCHEMBL19448939 | 0.70 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10PGRCHRM2 | |
| SCHEMBL16333390 | 0.69 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10TSHRGLA | |
| SCHEMBL14017058 | 0.68 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10PGRCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007149554-A2 | METHODS FOR RESTORING NEURAL FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2007-12-27 | — | — | WO | claimed |
| WO-2007149554-A2 | METHODS FOR RESTORING NEURAL FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2007-12-27 | — | — | WO | disclosed |