Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TPI1 | P60174 | 1/20 | 0.38 |
| ▸ | PGD | P52209 | 4/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10378936 | 0.85 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10GLACHRM5 | |
| SCHEMBL14019302 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10GLACHRM5 | |
| SCHEMBL7620877 | 0.82 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10GLACHRM5 | |
| SCHEMBL23286473 | 0.80 | TPI1 (0.33) | ALDH1A1LMNAHSD17B10TPI1PGD | |
| SCHEMBL13301617 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10GLACHRM5 | |
| SCHEMBL16075571 | 0.79 | PLA2G2A (0.37) | ALDH1A1LMNAHSD17B10GLACHRM5 | |
| SCHEMBL1068126 | 0.79 | TPI1 (0.41) | ALDH1A1TPI1PGDLPAR3LPAR1 | |
| SCHEMBL5329190 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10LPAR3LPAR1 | |
| SCHEMBL14414241 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10LPAR3LPAR1 | |
| SCHEMBL5665027 | 0.78 | LPAR3 (0.40) | ALDH1A1TPI1LPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658787-A | Neuronal stem cell differentiation | 加的夫大学学院咨询有限公司 | 2016-06-08 | — | — | CN | claimed |
| WO-2007149554-A2 | METHODS FOR RESTORING NEURAL FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2007-12-27 | — | — | WO | claimed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| WO-2017184871-A1 | CARBIDOPA AND L-DOPA PRODRUGS AND METHODS OF USE | ABBVIE INC. (US) | 2017-10-26 | — | — | WO | disclosed |
| US-20170283446-A1 | SOLUBLE C5aR ANTAGONISTS | CHEMOCENTRYX, INC. | 2017-10-05 | — | — | US | disclosed |
| US-20160264567-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | GENENTECH, INC. (US) | 2016-09-15 | — | — | US | disclosed |
| CN-105658787-A | Neuronal stem cell differentiation | 加的夫大学学院咨询有限公司 | 2016-06-08 | — | — | CN | disclosed |
| US-20160139136-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | WATERS TECHNOLOGIES CORPORATION (US) | 2016-05-19 | — | — | US | disclosed |
| US-20160139136-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | WATERS TECHNOLOGIES CORPORATION (US) | 2016-05-19 | — | — | US | disclosed |
| CN-104220053-A | Modulators of exchange proteins directly activated by camp (epacs) | UNIV TEXAS | 2014-12-17 | — | — | CN | disclosed |
| WO-2007149554-A2 | METHODS FOR RESTORING NEURAL FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2007-12-27 | — | — | WO | disclosed |
| US-5834436-A | CYCLOHEXANES SUBSTITUTED BY ACYLOXYALKYL PHOSPHATE ESTERS AS CARRIERS WHICH CAN PENETRATE CELL MEMBRANES WITHOUT DISRUPTING IT; | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-11-10 | — | — | US | disclosed |
| WO-1998026786-A1 | CAGED MEMBRANE-PERMEANT INOSITOL PHOSPHATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-06-25 | — | — | WO | disclosed |
| EP-0842181-A1 | MEMBRANE-PERMEANT SECOND MESSENGERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-05-20 | — | — | EP | disclosed |
| US-5693521-A | USING ACETOXYALKYL ESTER OF ADENOSINE(OR GUANOSINE)-3',5'-CYCLIC MONNOPHOSPHATE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-12-02 | — | — | US | disclosed |
| WO-1996040695-A1 | MEMBRANE-PERMEANT SECOND MESSENGERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1994023724-A1 | MEMBRANE-PERMEANT SECOND MESSENGERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-10-27 | — | — | WO | disclosed |
| US-4968788-A | DRUG DELIVERY, ANTITUMOR AGENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1990-11-06 | — | — | US | disclosed |
| WO-1990008155-A1 | BIOLOGICALLY REVERSIBLE PHOSPHATE AND PHOSPHONATE PROTECTIVE GROUPS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1990-07-26 | — | — | WO | disclosed |
| US-4816570-A | Biologically reversible phosphate and phosphonate protective groups | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 1989-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283446-A1 | SOLUBLE C5aR ANTAGONISTS | C5AR1, C3AR1, C5AR2 | ALDH1A1 2187/4885LMNA 3699/4885HSD17B10 4114/4885 |
| US-20160139136-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | FUT5, FUT6, CSGALNACT1 | ALDH1A1 4000/4885LMNA 1566/4885HSD17B10 4618/4885 |
| US-20160264567-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | TRPA1, TRPV1, TRPV5 | ALDH1A1 461/4885LMNA 2609/4885HSD17B10 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.