Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | BRD1 | O95696 | 2/20 | 0.43 |
| ▸ | TAF1 | P21675 | 2/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17200427 | 0.74 | LMNA (0.50) | LMNACA12CA1CA2CA9 | |
| SCHEMBL18932803 | 0.71 | MEN1 (0.46) | LMNACA12CA1CA2CA9 | |
| SCHEMBL14652569 | 0.70 | CYP2C9 (0.55) | LMNACA12CA1CA2CA9 | |
| SCHEMBL29159274 | 0.68 | TDP1 (0.49) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL17620197 | 0.67 | CA2 (1.00) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL30123663 | 0.65 | ANPEP (0.60) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL18485400 | 0.65 | ALDH1A1 (0.59) | LMNACA12CA9MEN1KMT2A | |
| SCHEMBL28517468 | 0.65 | ERCC1 (0.59) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL24453236 | 0.64 | ERCC1 (0.63) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL6005895 | 0.64 | ESR1 (0.62) | MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |