Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14520853 | 1.00 | KCNA5 (0.53) | KCNA5LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL210527 | 0.82 | KCNA5 (0.64) | KCNA5LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL15134850 | 0.79 | KCNA5 (0.69) | KCNA5LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL10282572 | 0.78 | KCNA5 (0.64) | KCNA5LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL10282859 | 0.77 | LMNA (0.62) | KCNA5LMNAKMT2A | |
| SCHEMBL27635088 | 0.76 | KCNA5 (0.60) | KCNA5LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL654947 | 0.75 | KCNA5 (0.59) | KCNA5LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL14520850 | 0.75 | SLC27A1 (0.60) | KMT2ASMN1; SMN2 | |
| SCHEMBL5338188 | 0.75 | SLC27A1 (0.60) | KMT2ASMN1; SMN2 | |
| SCHEMBL210449 | 0.75 | KCNA5 (0.59) | KCNA5LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045962-A2 | NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | claimed |
| US-20070088043-A1 | Novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED. (IN) | 2007-04-19 | — | — | US | claimed |
| WO-2007045962-A2 | NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | disclosed |
| US-20070088043-A1 | Novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED. (IN) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088043-A1 | Novel HDAC inhibitors | HDAC1, HDAC11, HDAC5 | KCNA5 3229/4885LMNA 1686/4885KMT2A 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.