Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1474880 | 0.86 | SMN1; SMN2 (0.54) | NEU3L3MBTL1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL28805203 | 0.86 | L3MBTL1 (0.55) | NEU3L3MBTL1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL29791318 | 0.86 | NEU3 (0.56) | NEU3L3MBTL1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL4176955 | 0.86 | NEU3 (0.56) | NEU3L3MBTL1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL29791247 | 0.86 | NEU3 (0.63) | NEU3L3MBTL1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL567311 | 0.86 | NEU3 (0.63) | NEU3L3MBTL1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL1473887 | 0.82 | NPC1 (0.47) | NEU3L3MBTL1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL3528076 | 0.81 | NEU3 (0.58) | NEU3KDM4EHSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL5322418 | 0.81 | NEU3 (0.58) | NEU3L3MBTL1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL5326622 | 0.81 | METAP2 (0.61) | L3MBTL1KDM4EHSD17B10KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220218678-A1 | USE OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES FOR TREATING CYSTIC FIBROSIS | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-07-14 | — | — | US | disclosed |
| WO-2020017934-A1 | COLORED CURABLE RESIN COMPOSITION, COLOR FILTER, AND DISPLAY APPARATUS | 동우 화인켐 주식회사 | 2020-01-23 | — | — | WO | disclosed |
| US-9132121-B2 | Dry powder formulation comprising a phosphodiesterase inhibitor | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-09-15 | — | — | US | disclosed |
| US-9051296-B2 | Aryl carboxamide derivatives as TTX-S blockers | RAQUALIA PHARMA INC. (JP) | 2015-06-09 | — | — | US | disclosed |
| US-9051296-B2 | Aryl carboxamide derivatives as TTX-S blockers | RAQUALIA PHARMA INC. (JP) | 2015-06-09 | — | — | US | disclosed |
| US-8648204-B2 | 1-phenyl-2-pyridinyl alkyl alcohol compounds as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-02-11 | — | — | US | disclosed |
| US-20120232052-A1 | ARYL CARBOXAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120232052-A1 | ARYL CARBOXAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-09-13 | — | — | US | disclosed |
| CN-101619065-B | Isoquinoline compound or salt thereof, medicinal composition, preparation method and application thereof | SHANGHAI INST PHARM INDUSTRY | 2012-07-25 | — | — | CN | disclosed |
| CN-101619065-A | Isoquinoline compound or salt thereof, medicinal composition, preparation method and application thereof | SHANGHAI INST PHARM INDUSTRY | 2010-01-06 | — | — | CN | disclosed |
| WO-2007144379-A1 | BICYCLIC COMPOUNDS USEFUL AS CATHEPSIN S INBHIBITORS | MEDIVIR AB (SE) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007144379-A1 | BICYCLIC COMPOUNDS USEFUL AS CATHEPSIN S INBHIBITORS | MEDIVIR AB (SE) | 2007-12-21 | — | — | WO | disclosed |
| WO-2006064286-A1 | CATHEPSIN S INHIBITORS | MEDIVIR UK LTD (GB) | 2006-06-22 | — | — | WO | disclosed |
| CN-1678594-A | Morpholin-acetamide derivatives for the treatment of inflammatory diseases | GLAXO GROUP LTD (GB) | 2005-10-05 | — | — | CN | disclosed |
| CN-1030409-A | Indole derivatives and preparation method thereof | GLAXO GROUP LTD (GB) | 1989-01-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220218678-A1 | USE OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES FOR TREATING CYSTIC FIBROSIS | CFTR, CLIC1, CLCN2 | NEU3 4324/4885L3MBTL1 2408/4885KDM4E 3618/4885 |
| US-20120232052-A1 | ARYL CARBOXAMIDE DERIVATIVES AS TTX-S BLOCKERS | SCN1B, SCN1A, SCN2B | NEU3 1690/4885L3MBTL1 3351/4885KDM4E 1141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.