Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.59 |
| ▸ | HTR2C | P28335 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | GPR183 | P32249 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | APLNR | P35414 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340169 | 1.00 | HTR2A (0.59) | HTR2AHTR2CCYP2C19OPRM1CYP1A2 | |
| SCHEMBL4211121 | 0.89 | OPRM1 (0.61) | OPRM1CHRM2CCR5UBE2MDCUN1D1 | |
| SCHEMBL7091708 | 0.89 | OPRM1 (0.61) | OPRM1CHRM2CCR5UBE2MDCUN1D1 | |
| SCHEMBL342508 | 0.89 | OPRM1 (0.56) | HTR2AHTR2CCYP2C19OPRM1CYP1A2 | |
| Hydrochloric Acid SCHEMBL4207721 | 0.88 | OPRM1 (0.60) | OPRM1CHRM2CCR5UBE2MDCUN1D1 | |
| SCHEMBL342509 | 0.88 | HTR2A (0.72) | HTR2AHTR2CCYP2C19OPRM1CYP1A2 | |
| Oxalic Acid SCHEMBL4208908 | 0.87 | OPRM1 (0.59) | OPRM1CHRM2CCR5UBE2MDCUN1D1 | |
| SCHEMBL341179 | 0.86 | CCR5 (0.55) | HTR2AHTR2CCYP2C19OPRM1CYP1A2 | |
| SCHEMBL341274 | 0.85 | UBE2M (0.65) | HTR2ACCR5UBE2MDCUN1D1 | |
| SCHEMBL10322397 | 0.85 | HTR2A (0.58) | HTR2ACYP2C19OPRM1KCNH2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124136-A1 | USE OF 4-AMINO-PIPERIDINES FOR TREATING SLEEP DISORDERS | ACADIA PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | WO | disclosed |