Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 2/20 | 0.31 |
| ▸ | LIPE | Q05469 | 4/20 | 0.31 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506374 | 1.00 | SCN9A (0.33) | SCN9AMGLLLMNAMAPTATM | |
| SCHEMBL5317212 | 0.92 | RXRA (0.33) | SCN9AMGLLLMNAMAPTATM | |
| SCHEMBL4507020 | 0.92 | RXRA (0.33) | SCN9AMGLLLMNAMAPTATM | |
| SCHEMBL4524286 | 0.91 | HTR1D (0.35) | SCN9AMGLLPOLQLIPEGCK | |
| SCHEMBL5329788 | 0.91 | HTR1D (0.35) | SCN9AMGLLPOLQLIPEGCK | |
| SCHEMBL13763360 | 0.88 | PIK3CA (0.31) | KDM4C | |
| SCHEMBL5370735 | 0.87 | LIPE (0.34) | SCN9AMGLLPOLQLIPE | |
| SCHEMBL5333522 | 0.87 | HSPB1 (0.36) | LMNAMAPTL3MBTL1KDM4C | |
| SCHEMBL4512372 | 0.87 | HSPB1 (0.36) | LMNAMAPTL3MBTL1KDM4C | |
| SCHEMBL4508563 | 0.82 | SCN9A (0.36) | SCN9ALIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |