Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27936402 | 0.98 | ALDH1A1 (0.54) | ALDH1A1CHRNB2CHRNB4CHRNA4HIF1A | |
| SCHEMBL2077373 | 0.93 | ALDH1A1 (0.54) | ALDH1A1CHRNB2CHRNB4CHRNA4HIF1A | |
| SCHEMBL28774714 | 0.91 | ALDH1A1 (0.52) | ALDH1A1CHRNB2CHRNB4CHRNA4HIF1A | |
| Hydrochloric Acid SCHEMBL8975960 | 0.89 | ALDH1A1 (0.50) | ALDH1A1CHRNB2CHRNB4CHRNA4HIF1A | |
| SCHEMBL15216471 | 0.86 | FAAH (0.50) | ALDH1A1MAPTLMNAFAAHTRPV1 | |
| SCHEMBL4721832 | 0.85 | — | — | |
| SCHEMBL9707391 | 0.84 | ALOX5 (0.43) | ALDH1A1HIF1ATSHRMAPTLMNA | |
| SCHEMBL23505875 | 0.80 | CNR1 (0.42) | ALDH1A1HIF1ATSHRMAPTLMNA | |
| SCHEMBL3113047 | 0.79 | ALDH1A1 (0.54) | ALDH1A1CHRNB2CHRNB4CHRNA4TSHR | |
| SCHEMBL5948495 | 0.79 | ALDH1A1 (0.74) | ALDH1A1CHRNB2CHRNB4CHRNA4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230050672-A1 | CATIONIC LIPID COMPOUNDS | TRANSLATE BIO, INC. | 2023-02-16 | — | — | US | disclosed |
| WO-2019055978-A1 | POLYOLEFIN DISPERSANTS AND METHODS OF MAKING AND USING THEREOF | CHEVRON ORONITE COMPANY LLC (US) | 2019-03-21 | — | — | WO | disclosed |
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230050672-A1 | CATIONIC LIPID COMPOUNDS | NPC1L1, NPC1, APMAP | ALDH1A1 3785/4885CHRNB2 3848/4885CHRNB4 4218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.