Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5433974 | 0.82 | — | — | |
| SCHEMBL9942573 | 0.73 | CCR1 (0.46) | CCR1CCR5CCR8 | |
| SCHEMBL23790563 | 0.64 | CCR1 (0.31) | CCR1CCR5CCR8 | |
| SCHEMBL25636036 | 0.64 | FFAR2 (0.37) | — | |
| SCHEMBL23133692 | 0.59 | CCNK (0.43) | — | |
| SCHEMBL25519645 | 0.58 | CCR1 (0.46) | CCR1CCR5CCR8 | |
| SCHEMBL21652566 | 0.58 | CCR1 (0.45) | CCR1CCR5CCR8 | |
| SCHEMBL18820441 | 0.58 | CHRM4 (0.32) | — | |
| SCHEMBL17828007 | 0.58 | UHRF1 (0.43) | CCR1CCR5CCR8 | |
| SCHEMBL1984578 | 0.58 | CCR1 (0.42) | CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007133756-A2 | CRF1 RECEPTOR LIGANDS COMPRISING HETEROARYL FUSED BICYCLES | NEUROGEN CORPORATION (US) | 2007-11-22 | — | — | WO | disclosed |