Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20894092 | 0.81 | SMN1; SMN2 (0.69) | SMN1; SMN2TSHRGAAHPGDKMT2A | |
| SCHEMBL5327218 | 0.78 | PTGDR2 (0.43) | SMN1; SMN2PTGDR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL18059154 | 0.74 | ALDH1A1 (0.32) | TSHRHPGDALDH1A1 | |
| SCHEMBL14109405 | 0.74 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRGAAHPGDKMT2A | |
| SCHEMBL27727783 | 0.73 | CDC7 (0.47) | SMN1; SMN2HDAC1HDAC6HDAC8PTGDR2 | |
| SCHEMBL14109812 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAKMT2ANPC1RAB9A | |
| SCHEMBL5551869 | 0.72 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRGAAHPGDKMT2A | |
| SCHEMBL4032013 | 0.72 | KLKB1 (0.56) | SMN1; SMN2TSHRGAAHPGDNPC1 | |
| SCHEMBL19207619 | 0.71 | TSHR (0.56) | SMN1; SMN2HDAC6TSHRKMT2AMEN1 | |
| SCHEMBL14345711 | 0.71 | PTGDR2 (0.69) | SMN1; SMN2PTGDR2HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |