Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 0.69 |
| ▸ | CA1 | P00915 | 8/20 | 0.69 |
| ▸ | CA2 | P00918 | 8/20 | 0.69 |
| ▸ | CA9 | Q16790 | 8/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.52 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12681731 | 0.78 | CA12 (0.69) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3342878 | 0.77 | ALDH1A1 (1.00) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL5334816 | 0.76 | KDM4E (0.78) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL9953988 | 0.74 | CA12 (0.68) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL2730392 | 0.72 | CA12 (0.64) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL31597390 | 0.71 | PDE7A (0.68) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL30082253 | 0.71 | KDM4E (0.49) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL9955792 | 0.71 | ALDH1A1 (0.73) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL18708211 | 0.71 | ALDH1A1 (0.55) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6980347 | 0.71 | KDM4E (1.00) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028789-A1 | QUINAZOLINE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-03-15 | — | — | WO | disclosed |