Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.78 |
| ▸ | GAA | P10253 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 4/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480237 | 0.91 | MEN1 (0.73) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6980347 | 0.88 | KDM4E (1.00) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5333099 | 0.80 | KDM4E (0.59) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10743256 | 0.78 | KDM4E (0.73) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8883239 | 0.78 | KMT2A (0.63) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5329928 | 0.76 | CA12 (0.69) | KDM4EGAAALDH1A1L3MBTL1CA9 | |
| SCHEMBL31145272 | 0.76 | MAT2A (0.76) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22093264 | 0.76 | MAT2A (0.76) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9799805 | 0.75 | KDM4E (0.59) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6974482 | 0.75 | KDM4E (0.78) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028789-A1 | QUINAZOLINE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-03-15 | — | — | WO | claimed |
| WO-2007028789-A1 | QUINAZOLINE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-03-15 | — | — | WO | disclosed |