Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 4/20 | 0.58 |
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | CA9 | Q16790 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.53 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.52 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6282946 | 0.86 | ALDH1A1 (0.71) | ALDH1A1RXFP1L3MBTL1PKMCA12 | |
| SCHEMBL3342878 | 0.84 | ALDH1A1 (1.00) | ALDH1A1RXFP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL5425840 | 0.77 | ALDH1A1 (0.59) | ALDH1A1RXFP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL9953957 | 0.77 | ALDH1A1 (0.67) | ALDH1A1RXFP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL22191252 | 0.74 | AKT2 (0.47) | ALDH1A1RXFP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL29437804 | 0.74 | AKT2 (0.47) | ALDH1A1RXFP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL3336450 | 0.74 | ALDH1A1 (0.71) | ALDH1A1RXFP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL9953988 | 0.74 | CA12 (0.68) | ALDH1A1RXFP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL3341796 | 0.73 | ALDH1A1 (0.66) | ALDH1A1RXFP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL31519931 | 0.72 | GAA (0.59) | ALDH1A1PKMCA12CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |