Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1349845 | 0.85 | CA12 (0.42) | SLC6A9ARMAP2K1POLBRAB9A | |
| SCHEMBL5329614 | 0.84 | MAP2K1 (0.47) | SLC6A9ARMAP2K1MEN1KMT2A | |
| SCHEMBL842185 | 0.80 | SLC6A9 (0.47) | SLC6A9 | |
| SCHEMBL3019239 | 0.78 | CYP3A4 (0.42) | SLC6A9MAP2K1MEN1KMT2ARAB9A | |
| SCHEMBL23327273 | 0.71 | CYP3A4 (0.53) | MAP2K1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11540305 | 0.70 | CYP3A4 (0.49) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL18134157 | 0.70 | LMNA (0.41) | MEN1KMT2APOLBRAB9ASMN1; SMN2 | |
| SCHEMBL14992759 | 0.68 | SMN1; SMN2 (0.46) | MAP2K1MEN1KMT2APOLBRAB9A | |
| SCHEMBL11519119 | 0.67 | ERN1 (0.47) | MEN1KMT2APOLBRAB9ASMN1; SMN2 | |
| SCHEMBL9713491 | 0.67 | CYP3A4 (0.58) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147834-A1 | GLYCINE TRANSPORTER INHIBITING COMPOUNDS AND USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-12-27 | — | — | WO | disclosed |