Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1349845 | 0.85 | CA12 (0.42) | MAP2K1ARSLC6A9POLBKDM4E | |
| SCHEMBL5329932 | 0.84 | SLC6A9 (0.39) | MAP2K1ARSLC6A9POLBMEN1 | |
| SCHEMBL12439663 | 0.80 | SLC6A9 (0.46) | SLC6A9 | |
| SCHEMBL5329670 | 0.78 | MAP2K1 (0.50) | MAP2K1SLC6A9POLBL3MBTL1KDM4E | |
| SCHEMBL5329470 | 0.73 | CA12 (0.52) | ARPOLBL3MBTL1KDM4ECTDSP1 | |
| SCHEMBL23327273 | 0.71 | CYP3A4 (0.53) | MAP2K1KMT2AALDH1A1RAB9AHTT | |
| SCHEMBL21671633 | 0.68 | CA12 (0.44) | MAP2K1L3MBTL1KDM4EALDH1A1RAB9A | |
| SCHEMBL4153927 | 0.67 | CYP3A4 (0.58) | POLBL3MBTL1KDM4ECTDSP1TDP1 | |
| SCHEMBL11850840 | 0.67 | TSHR (0.59) | POLBL3MBTL1KDM4ECTDSP1TDP1 | |
| SCHEMBL1004368 | 0.67 | ACHE (0.48) | POLBL3MBTL1KDM4ECTDSP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147834-A1 | GLYCINE TRANSPORTER INHIBITING COMPOUNDS AND USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-12-27 | — | — | WO | disclosed |