Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 8/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CACNA2D1 | P54289 | 8/20 | 0.62 |
| ▸ | CACNB1 | Q02641 | 8/20 | 0.62 |
| ▸ | CACNA1B | Q00975 | 6/20 | 0.62 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.62 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5362020 | 0.97 | CACNA1G (0.63) | CACNA1GLMNACACNA2D1CACNB1CACNA1B | |
| SCHEMBL5325048 | 0.90 | CACNA1G (0.60) | CACNA1GLMNACACNA2D1CACNB1CACNA1B | |
| SCHEMBL5329843 | 0.88 | CACNA2D1 (0.61) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5356025 | 0.87 | CACNA1G (0.56) | CACNA1GLMNACACNA2D1CACNB1CACNA1B | |
| SCHEMBL5372531 | 0.85 | CACNA1G (0.66) | CACNA1GLMNACACNA2D1CACNB1CACNA1B | |
| SCHEMBL5360610 | 0.85 | CACNA2D1 (0.57) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5331579 | 0.80 | CACNA1G (0.64) | CACNA1GLMNACACNA2D1CACNB1CACNA1B | |
| SCHEMBL8427763 | 0.78 | CACNA2D1 (1.00) | CACNA1GLMNACACNA2D1CACNB1CACNA1B | |
| SCHEMBL5265363 | 0.78 | CACNA2D1 (1.00) | CACNA1GLMNACACNA2D1CACNB1CACNA1B | |
| SCHEMBL5324471 | 0.76 | CACNA2D1 (0.61) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | claimed |
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | disclosed |