Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 11/20 | 0.57 |
| ▸ | CACNB1 | Q02641 | 11/20 | 0.57 |
| ▸ | CACNA1B | Q00975 | 10/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 7/20 | 0.57 |
| ▸ | CACNA1G | O43497 | 9/20 | 0.52 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329843 | 0.97 | CACNA2D1 (0.61) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL14344630 | 0.89 | CACNA2D1 (0.54) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5362020 | 0.89 | CACNA1G (0.63) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5356025 | 0.86 | CACNA1G (0.56) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5329966 | 0.85 | CACNA1G (0.67) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5361400 | 0.83 | CACNA2D1 (0.55) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5325048 | 0.82 | CACNA1G (0.60) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL7597098 | 0.79 | CACNA2D1 (0.64) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5333695 | 0.77 | CACNA2D1 (0.58) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5324471 | 0.74 | CACNA2D1 (0.61) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | claimed |
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | disclosed |