Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 6/20 | 0.64 |
| ▸ | GPX4 | P36969 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TACR3 | P29371 | 1/20 | 0.56 |
| ▸ | CACNA2D1 | P54289 | 8/20 | 0.53 |
| ▸ | CACNB1 | Q02641 | 8/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 6/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351830 | 0.90 | TACR3 (0.59) | CACNA1GGPX4TACR3CACNA2D1CACNB1 | |
| SCHEMBL5326872 | 0.90 | TACR3 (0.59) | CACNA1GGPX4TACR3CACNA2D1CACNB1 | |
| SCHEMBL5365428 | 0.87 | LMNA (0.52) | CACNA1GGPX4LMNACACNA2D1CACNB1 | |
| SCHEMBL5357281 | 0.87 | LMNA (0.52) | CACNA1GGPX4LMNACACNA2D1CACNB1 | |
| SCHEMBL5329966 | 0.80 | CACNA1G (0.67) | CACNA1GLMNACACNA2D1CACNB1CACNA1B | |
| SCHEMBL5372531 | 0.80 | CACNA1G (0.66) | CACNA1GLMNACACNA2D1CACNB1CACNA1B | |
| SCHEMBL5324722 | 0.78 | TACR3 (0.58) | CACNA1GGPX4LMNATACR3CACNA2D1 | |
| SCHEMBL5362020 | 0.78 | CACNA1G (0.63) | CACNA1GLMNACACNA2D1CACNB1CACNA1B | |
| SCHEMBL5329875 | 0.76 | CA1 (0.50) | GPX4LMNACACNA2D1CACNB1CACNA1B | |
| SCHEMBL16598473 | 0.75 | TACR3 (0.67) | CACNA1GTACR3CACNA2D1CACNB1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | disclosed |