Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | F10 | P00742 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | LSS | P48449 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327658 | 0.84 | L3MBTL1 (0.42) | ATML3MBTL1F10LMNATDP1 | |
| SCHEMBL5323222 | 0.83 | L3MBTL1 (0.47) | ATML3MBTL1F10LMNATDP1 | |
| SCHEMBL5324555 | 0.83 | ATM (0.63) | ATML3MBTL1F10LMNATDP1 | |
| SCHEMBL5296078 | 0.82 | HRH3 (0.52) | ATML3MBTL1F10TDP1MEN1 | |
| SCHEMBL5193868 | 0.80 | ATM (0.71) | ATML3MBTL1F10LMNALSS | |
| Hydrochloric Acid SCHEMBL6195419 | 0.79 | ATM (0.69) | ATML3MBTL1F10LMNALSS | |
| SCHEMBL4893575 | 0.77 | F10 (0.68) | F10LSSSMN1; SMN2 | |
| SCHEMBL5733762 | 0.76 | F10 (0.72) | ATML3MBTL1F10LMNASMN1; SMN2 | |
| SCHEMBL4884832 | 0.75 | F10 (0.55) | F10LMNALSSSMN1; SMN2MAPT | |
| SCHEMBL1946614 | 0.75 | L3MBTL1 (0.75) | ATML3MBTL1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008145-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | claimed |
| WO-2007008145-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |