Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323222 | 0.85 | L3MBTL1 (0.47) | L3MBTL1TDP1F10ATMMAPT | |
| SCHEMBL5327115 | 0.84 | GHSR (0.50) | L3MBTL1TDP1F10ATMMAPT | |
| SCHEMBL5330111 | 0.84 | ATM (0.54) | L3MBTL1TDP1F10ATMMAPT | |
| SCHEMBL5296078 | 0.83 | HRH3 (0.52) | L3MBTL1TDP1F10ATMMAPT | |
| SCHEMBL5093870 | 0.75 | F10 (0.66) | F10 | |
| SCHEMBL5323125 | 0.74 | HRH3 (0.51) | L3MBTL1TDP1F10MAPTLMNA | |
| SCHEMBL5326485 | 0.73 | ALDH1A1 (0.48) | L3MBTL1F10ATMMAPTMEN1 | |
| SCHEMBL6151827 | 0.72 | F10 (0.63) | F10ATMMAPT | |
| SCHEMBL5733653 | 0.70 | F10 (0.57) | F10ATM | |
| SCHEMBL5327745 | 0.70 | MAPT (0.52) | L3MBTL1F10MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008145-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | claimed |
| WO-2007008145-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |